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The global demand for lithopone has been steadily increasing in recent years, driven by the growth of the construction, automotive, and electronics industries
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    The risks associated with titanium dioxide exposure depend on a variety of factors, including the form of the mineral, the route of exposure (such as being inhaled or consumed), and the duration and intensity of exposure.

    In a 2022 study published in the Journal of Hazardous Materials, scientists wanted to examine the effects of titanium dioxide as a food additive on atherosclerosis in mice. (Atherosclerosis refers to a hardening of the arteries.) Researchers fed mice 40 mg/kg of the food additive every day for 4 months, and found that it not only altered gut microbiota but also led to a significantly increased atherosclerotic lesion area, especially in animals that consumed a high-choline western diet (HCD).
    aqueous solution of the desired grade of lithopone while the by-product remains in solution, from which it may be recovered by treating in a suitable manner.
     
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